Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Broussonin A SCHEMBL774802 | 0.82 | ESR1 (1.00) | ESR1CYP19A1ESR2POLBCALM1 | |
| SCHEMBL1734687 | 0.77 | NPC1 (0.52) | POLBALOX15DAOL3MBTL1 | |
| Broussonin E SCHEMBL31510414 | 0.77 | CYP19A1 (0.74) | ESR1CYP19A1ESR2POLBCALM1 | |
| Broussonin E SCHEMBL6825353 | 0.77 | CYP19A1 (0.74) | ESR1CYP19A1ESR2POLBCALM1 | |
| SCHEMBL29290893 | 0.74 | ESR1 (0.69) | ESR1CYP19A1ESR2POLBCALM1 | |
| SCHEMBL5756628 | 0.74 | CYP4A11 (0.45) | ALOX15DAOFFAR4L3MBTL1CASP3 | |
| SCHEMBL30380929 | 0.74 | CYP4A11 (0.45) | ALOX15DAOFFAR4L3MBTL1CASP3 | |
| SCHEMBL227115 | 0.74 | ESR1 (0.73) | ESR1CYP19A1ESR2POLBCALM1 | |
| SCHEMBL28957723 | 0.74 | ESR1 (0.69) | ESR1CYP19A1ESR2POLBCALM1 | |
| SCHEMBL27633878 | 0.74 | ESR1 (0.69) | ESR1CYP19A1ESR2POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259689-A1 | FLAVOR MOLECULES | Givaudan SA (CH) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009105906-A1 | FLAVOR MOLECULES | GIVAUDAN SA (CH) | 2009-09-03 | — | — | WO | disclosed |