Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756628 | 1.00 | CYP4A11 (0.45) | CYP4A11NNMTCYP11B1CYP11B2TNKS2 | |
| Lithium Ion SCHEMBL29886630 | 0.97 | CYP4A11 (0.42) | CYP4A11NNMTCYP11B1CYP11B2TNKS2 | |
| SCHEMBL20577121 | 0.95 | CYP4A11 (0.46) | CYP4A11NNMTCASP3SENP8SENP7 | |
| SCHEMBL3229511 | 0.89 | NNMT (0.44) | CYP4A11NNMTCYP11B1GRM2CYP4F2 | |
| SCHEMBL16797047 | 0.84 | KDM4E (0.44) | NNMTCYP11B1CASP3SENP8SENP7 | |
| SCHEMBL13791527 | 0.84 | CASP3 (0.53) | CASP3SENP8SENP7SENP6KDM1A | |
| SCHEMBL30381134 | 0.84 | KDM4E (0.44) | NNMTCYP11B1CASP3SENP8SENP7 | |
| SCHEMBL25296019 | 0.82 | CASP3 (0.41) | NNMTCYP11B1CASP3SENP8SENP7 | |
| SCHEMBL20759038 | 0.82 | CASP3 (0.59) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL16444063 | 0.82 | CASP3 (0.41) | NNMTCYP11B1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075512-A | Heterocyclic compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-05 | — | — | CN | disclosed |