Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27906655 | 0.88 | OPRL1 (0.40) | GNAI3GNAO1GNAI1OPRL1 | |
| SCHEMBL1114793 | 0.80 | EPHX1 (0.64) | PRCPEPHX1EPHX2 | |
| SCHEMBL24736431 | 0.79 | OPRL1 (0.48) | GNAI3GNAO1GNAI1OPRL1 | |
| SCHEMBL1114636 | 0.77 | CCR2 (0.57) | GNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL13386883 | 0.77 | GNAI3 (0.47) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL9980449 | 0.76 | S1PR4 (0.46) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL1114595 | 0.76 | PSEN1 (0.38) | CCR2 | |
| SCHEMBL1114533 | 0.76 | PSEN1 (0.38) | CCR2 | |
| SCHEMBL1114672 | 0.76 | CCR2 (0.60) | GNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL1114932 | 0.76 | CCR2 (0.60) | GNAI3GNAO1GNAI1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781299-B1 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTPR LTD (GB) | 2010-12-22 | — | — | EP | disclosed |