SCHEMBL343587

SCHEMBL343587

CCOC(=O)c1cccc(P(=O)(O)O)c1C(=O)OCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
PTK2B Q14289 3/20 0.46
CDC25B P30305 3/20 0.46
RXFP1 Q9HBX9 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 2/20 0.44
MAPT P10636 3/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4042331 0.85 TSHR (0.67) TSHRALDH1A1HSD17B10PTK2BCDC25B
SCHEMBL560709 0.83 TSHR (0.73) TSHRCA12CA1CA2CA7
SCHEMBL343035 0.79 CA1 (0.48) TSHRCA12CA1CA2CA7
SCHEMBL302145 0.78 TSHR (0.66) TSHRCA12CA1CA2CA7
SCHEMBL10882650 0.77 CA12 (0.82) TSHRCA12CA1CA2CA7
SCHEMBL2137984 0.77 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL27523216 0.77 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL11521675 0.76 TSHR (0.68) TSHRCA12CA1CA2CA7
SCHEMBL4626397 0.76 TSHR (0.61) TSHRCA12CA1CA2CA7
SCHEMBL4625647 0.76 TSHR (0.61) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029108-B1 POLYLACTIC ACID RESIN COMPOSITION KAO CORP (JP) 2020-04-22 EP disclosed
EP-3089472-B1 VIBRATION DAMPING MATERIAL KAO CORP (JP) 2018-10-31 EP disclosed
EP-2975089-B1 POLYLACTIC ACID RESIN COMPOSITION KAO CORP (JP) 2018-10-17 EP disclosed
US-10100191-B2 Polylactic acid resin composition KAO CORPORATION (JP) 2018-10-16 US disclosed
EP-2310454-B1 BIODEGRADABLE RESIN COMPOSITION KAO CORP (JP) 2017-10-04 EP disclosed
US-9721555-B2 Vibration damping material KAO CORPORATION (JP) 2017-08-01 US disclosed
EP-2272913-B1 MANUFACTURING METHOD FOR POLYLACTIC ACID RESIN COMPOSITIONS KAO CORP (JP) 2017-04-26 EP disclosed
US-9550876-B2 Polylactic acid resin composition and polylactic acid resin molded body NEC CORPORATION (JP) 2017-01-24 US disclosed
US-9505913-B2 Polylactic acid resin composition KAO CORPORATION (JP) 2016-11-29 US disclosed
EP-3089472-A1 VIBRATION DAMPING MATERIAL Kao Corporation (JP) 2016-11-02 EP disclosed
US-20100331446-A1 BIODEGRADABLE RESIN COMPOSITION TAKENAKA AKIRA 2010-12-30 US disclosed
EP-2264103-A1 POLYLACTIC ACID RESIN COMPOSITE Kao Corporation (JP) 2010-12-22 EP disclosed
US-7812066-B2 Biodegradable resin composition KAO CORPORATION (JP) 2010-10-12 US disclosed
US-20100210756-A1 BIODEGRADABLE RESIN COMPOSITION TAKENAKA AKIRA 2010-08-19 US disclosed
US-20100201037-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORPORATION (JP) 2010-08-12 US disclosed
EP-2199052-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN Kao Corporation (JP) 2010-06-23 EP disclosed
US-20100063177-A1 BIODEGRADABLE RESIN COMPOSITION KAO CORPORATION (JP) 2010-03-11 US disclosed
WO-2010016619-A1 BIODEGRADABLE RESIN COMPOSITION KAO CORPORATIOIN (JP) 2010-02-11 WO disclosed
WO-2010010961-A1 BIODEGRADABLE RESIN COMPOSITION KAO CORPORATION (JP) 2010-01-28 WO disclosed
EP-2067822-A1 BIODEGRADABLE RESIN COMPOSITION Kao Corporation (JP) 2009-06-10 EP disclosed