SCHEMBL560709

SCHEMBL560709

CCOC(=O)c1cccc(C(=O)OCC)c1C(=O)OCC

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.73
CA12 O43570 3/20 0.68
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
CA7 P43166 3/20 0.68
CA9 Q16790 3/20 0.68
CA14 Q9ULX7 3/20 0.68
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 3/20 0.61
CDC25B P30305 3/20 0.56
CYP1A2 P05177 2/20 0.55
MAPT P10636 3/20 0.51
CLEC4M Q9H2X3 1/20 0.51
CDC25A P30304 1/20 0.51
CDC25C P30307 1/20 0.51
MEN1 O00255 1/20 0.51
USP2 O75604 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27523216 0.93 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL302145 0.90 TSHR (0.66) TSHRCA12CA1CA2CA7
SCHEMBL11296630 0.89 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL10882650 0.89 CA12 (0.82) TSHRCA12CA1CA2CA7
SCHEMBL2137984 0.89 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL11521675 0.88 TSHR (0.68) TSHRCA12CA1CA2CA7
SCHEMBL28620465 0.88 TSHR (0.70) TSHRCA12CA1CA2CA7
SCHEMBL28620461 0.88 TSHR (0.70) TSHRCA12CA1CA2CA7
SCHEMBL2894636 0.87 ALDH1A1 (0.72) TSHRCA12CA1CA2CA7
SCHEMBL4625647 0.87 TSHR (0.61) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917976-B1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-04-15 EP claimed
US-12091474-B2 Method for producing polydienes with reduced cold flow BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2024-09-17 US claimed
CN-115806638-A Catalyst system for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-03-17 CN claimed
CN-115806635-A Catalyst system for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-03-17 CN claimed
US-20220106421-A1 Method For Producing Polydienes With Reduced Cold Flow BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-04-07 US claimed
CN-109772379-B Nano-scale metal fluoride catalyst with limited domain structure and preparation method and application thereof 浙江工业大学 2021-12-14 CN claimed
CN-113412286-A Process for preparing polydienes having reduced cold flow properties 普利司通美国轮胎运营有限责任公司 2021-09-17 CN claimed
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
CN-112011201-A Compressor surface treating agent and anti-corrosion treatment method 蚌埠艾普压缩机制造有限公司 2020-12-01 CN claimed
CN-111548658-A Steel pipe surface treating agent and anti-corrosion treatment method 安徽唐道电子科技有限公司 2020-08-18 CN claimed
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US claimed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US claimed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US claimed
US-9951157-B2 Spherical carriers for olefin polymerization catalyst, catalyst components, catalyst, and preparation methods therefor CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-04-24 US claimed
US-20160251457-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-01 US claimed
EP-3059263-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
EP-3917976-B1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-04-15 EP disclosed
US-12410274-B2 Anionic dispersion polymerization process to make random copolymer rubber BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20060003888-A1 Spheric catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-01-05 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 TSHR 2785/4885CA12 1643/4885CA1 2225/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 TSHR 2874/4885CA12 782/4885CA1 862/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 TSHR 2785/4885CA12 1643/4885CA1 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.