SCHEMBL4042331

SCHEMBL4042331

CCOC(=O)c1ccccc1P(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.67
PTK2B Q14289 2/20 0.60
RXFP1 Q9HBX9 1/20 0.60
HSD17B10 Q99714 4/20 0.57
ALDH1A1 P00352 3/20 0.57
CDC25B P30305 1/20 0.49
NPSR1 Q6W5P4 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
HTT P42858 2/20 0.48
TP53 P04637 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 4/20 0.47
LMNA P02545 3/20 0.47
MAPK10 P53779 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28817719 0.85 TSHR (0.61) TSHRPTK2BRXFP1HSD17B10ALDH1A1
SCHEMBL343587 0.85 TSHR (0.56) TSHRPTK2BRXFP1HSD17B10ALDH1A1
SCHEMBL6182233 0.83 TSHR (0.62) TSHRHSD17B10ALDH1A1CDC25BNPSR1
SCHEMBL11655079 0.82 TSHR (0.61) TSHRHSD17B10ALDH1A1CDC25BNPSR1
SCHEMBL11656059 0.82 TSHR (0.61) TSHRHSD17B10ALDH1A1CDC25BNPSR1
Diethyl Phthalate SCHEMBL22296 0.81 TSHR (1.00) TSHRPTK2BHSD17B10ALDH1A1CDC25B
Diethyl Phthalate SCHEMBL29404255 0.81 TSHR (1.00) TSHRPTK2BHSD17B10ALDH1A1CDC25B
Diethyl Phthalate SCHEMBL5306972 0.81 TSHR (1.00) TSHRPTK2BHSD17B10ALDH1A1CDC25B
SCHEMBL16047528 0.81 TSHR (0.59) TSHRHSD17B10ALDH1A1CDC25BNPSR1
SCHEMBL11652038 0.81 TSHR (0.59) TSHRHSD17B10ALDH1A1CDC25BNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2927279-A1 FLAME-RETARDANT POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION, AND MOLDED PRODUCT THEREOF Wintech Polymer Ltd. (JP) 2015-10-07 EP disclosed
EP-1486536-B2 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-10-10 EP disclosed
US-7498375-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2009-03-03 US disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
EP-1486536-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2007-01-24 EP disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 US disclosed
US-20050004292-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-01-06 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1486536-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-12-15 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed