Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 8/20 | 0.38 |
| ▸ | AOC1 | P19801 | 7/20 | 0.38 |
| ▸ | LOX | P28300 | 2/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972373 | 0.80 | LOXL2 (0.47) | LOXL2AOC3AOC1LOXLOXL3 | |
| SCHEMBL1211562 | 0.80 | KDM4E (0.39) | LOXL2 | |
| SCHEMBL13029050 | 0.77 | LOXL2 (0.44) | LOXL2AOC3AOC1LOXLOXL3 | |
| SCHEMBL25199133 | 0.77 | LOXL2 (0.39) | LOXL2LOXLOXL3DPP4 | |
| SCHEMBL25197333 | 0.77 | NOS2 (0.47) | LOXL2AOC3LOXLOXL3DPP4 | |
| SCHEMBL8930770 | 0.76 | LOXL2 (0.45) | LOXL2AOC3AOC1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL25196993 | 0.75 | LOXL2 (0.38) | LOXL2LOXLOXL3DPP4 | |
| SCHEMBL19322914 | 0.71 | CARM1 (0.41) | LOXL2DPP4 | |
| SCHEMBL1146338 | 0.71 | — | — | |
| SCHEMBL29505683 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252605-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009095872-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-08-06 | — | — | WO | disclosed |