Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079844 | 0.95 | GPR119 (0.49) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL3435468 | 0.90 | MEN1 (0.48) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL3435948 | 0.87 | USP30 (0.49) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL16105020 | 0.82 | EPHX1 (0.49) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL4186514 | 0.82 | HPGD (0.57) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL4186516 | 0.82 | HPGD (0.57) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL4186518 | 0.82 | HPGD (0.57) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL13634197 | 0.81 | EPHX1 (0.48) | HPGDEPHX1GPR119MEN1KMT2A | |
| SCHEMBL16993001 | 0.80 | EPHX1 (0.50) | HPGDEPHX1GPR119ALDH1A1MAPT | |
| SCHEMBL2953243 | 0.79 | EPHX1 (0.58) | HPGDEPHX1GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HPGD 1166/4885EPHX1 2942/4885GPR119 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.