Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105020 | 0.87 | EPHX1 (0.49) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL2079844 | 0.86 | GPR119 (0.49) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL16095809 | 0.85 | GPR119 (0.46) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL16993001 | 0.84 | EPHX1 (0.50) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL13811514 | 0.84 | GPR119 (0.52) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL3435952 | 0.81 | HPGD (0.49) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL7065136 | 0.81 | GPR119 (0.48) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL1830482 | 0.81 | HPGD (0.48) | EPHX1HPGDGPR119RECQLJAK2 | |
| SCHEMBL4711418 | 0.80 | HPGD (0.55) | EPHX1HPGDGPR119RECQLUSP30 | |
| SCHEMBL2997791 | 0.79 | GPR119 (0.50) | EPHX1HPGDGPR119RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |