Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436843 | 0.87 | MEN1 (0.45) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL3435639 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4412154 | 0.78 | LMNA (0.56) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL3435121 | 0.78 | USP8 (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL3434270 | 0.75 | GAA (0.46) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL3436844 | 0.73 | LMNA (0.42) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4393525 | 0.72 | MEN1 (0.64) | MEN1KMT2AGAAMAPK1L3MBTL1 | |
| SCHEMBL4395587 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL3435589 | 0.70 | GAA (0.43) | ALDH1A1KDM4EGAASMN1; SMN2HTT | |
| SCHEMBL3436304 | 0.70 | POLB (0.48) | ALDH1A1MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885MEN1 4778/4885KMT2A 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.