Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664707 | 0.83 | HSD17B10 (0.56) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL3436342 | 0.80 | ALDH1A1 (0.56) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL30683883 | 0.79 | GAA (0.64) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL29113608 | 0.79 | GAA (0.64) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL3554546 | 0.78 | KDM4E (0.51) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL581026 | 0.78 | GAA (0.67) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL12752917 | 0.77 | HSD17B10 (0.57) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL2303906 | 0.76 | HSD17B10 (0.55) | HSD17B10KDM4EGAAPOLBNR4A1 | |
| SCHEMBL2772004 | 0.76 | ALDH1A1 (0.56) | HSD17B10KDM4EGAAPOLBMYC | |
| SCHEMBL3436343 | 0.74 | ADAM10 (0.41) | KDM4EGAANR4A1HTR7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HSD17B10 4247/4885KDM4E 1834/4885GAA 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.