Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436347 | 0.91 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL3436344 | 0.88 | HTR7 (0.46) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL3436340 | 0.80 | POLB (0.64) | ALDH1A1POLBKMT2AMAPTCYP1A2 | |
| SCHEMBL3436342 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL2557677 | 0.77 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL3436317 | 0.76 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL3436339 | 0.75 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL14804170 | 0.75 | ALDH1A1 (0.64) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL3434251 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL14804173 | 0.74 | GAA (0.50) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885POLB 4512/4885SMN1; SMN2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.