Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436605 | 0.93 | ACKR3 (0.42) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436607 | 0.93 | ACKR3 (0.42) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436864 | 0.88 | ACKR3 (0.41) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436586 | 0.86 | POLB (0.47) | GAAHPGDMEN1KMT2APOLB | |
| SCHEMBL3436845 | 0.86 | ACKR3 (0.41) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436606 | 0.85 | HRH3 (0.48) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436416 | 0.84 | L3MBTL1 (0.53) | KMT2AL3MBTL1 | |
| SCHEMBL5723738 | 0.83 | OGA (0.49) | ACKR3GAAHPGDHRH3POLB | |
| SCHEMBL3436842 | 0.83 | HRH3 (0.44) | ACKR3GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL3436849 | 0.80 | GAA (0.42) | ACKR3GAAHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ACKR3 224/4885GAA 3904/4885KDM4E 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.