SCHEMBL5723738

SCHEMBL5723738

CNC(=O)c1csc(N2CCC(O)CC2)n1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OGA O60502 2/20 0.49
HRH3 Q9Y5N1 3/20 0.44
ACKR3 P25106 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5723711 0.86 OGA (0.46) OGAACKR3L3MBTL1HPGDRAB9A
SCHEMBL5723678 0.84 HRH3 (0.46) OGAHRH3ACKR3
SCHEMBL5723961 0.83 OGA (0.45) OGAHRH3ACKR3L3MBTL1HPGD
SCHEMBL3436588 0.83 ACKR3 (0.43) OGAHRH3ACKR3L3MBTL1HPGD
SCHEMBL2078959 0.82 PTGER1 (0.48) OGAHRH3L3MBTL1RAB9ANPC1
SCHEMBL5724211 0.81 HRH3 (0.56) OGAHRH3L3MBTL1RAB9ANPC1
SCHEMBL5723977 0.81 OGA (0.49) OGAHRH3RAB9ANPC1
SCHEMBL5724404 0.80 HRH3 (0.47) OGAHRH3ACKR3L3MBTL1
SCHEMBL13270342 0.79 HRH3 (0.41) HRH3L3MBTL1RAB9ANPC1
SCHEMBL5723882 0.77 OGA (0.52) OGAHRH3L3MBTL1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD OGA 3469/4885HRH3 3678/4885ACKR3 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.