SCHEMBL3436700

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3435491	0.85	HSP90AA1 (0.44)	MAPTLMNATP53ALDH1A1KDM4E
	SCHEMBL3436696	0.82	PTGDR2 (0.50)	CYP1A2MAPTTP53NPC1ALDH1A1
	SCHEMBL14960103	0.79	CYP1A1 (0.55)	CYP1A1CYP1B1CYP1A2CYP3A4CYP2E1
	SCHEMBL28295525	0.79	ALOX5 (0.60)	MAPTLMNATP53
	SCHEMBL4296288	0.78	MAPT (0.39)	CYP2C9MAPTTP53NPC1ALDH1A1
	SCHEMBL3435518	0.78	SMN1; SMN2 (0.51)	CYP1A1CYP1B1CYP1A2CYP3A4CYP2E1
	SCHEMBL3372237	0.77	MAPT (0.55)	MAPTLMNATP53ALDH1A1HPGD
	SCHEMBL2764145	0.73	MAPT (0.54)	MAPTLMNATP53ALDH1A1RXFP1
	SCHEMBL19936773	0.73	HSP90AA1 (0.45)	MAPTLMNATP53ALDH1A1KDM4E
	SCHEMBL19936482	0.73	CYP1A1 (0.48)	CYP1A1CYP1B1CYP1A2CYP3A4CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.