Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436696 | 0.85 | PTGDR2 (0.50) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL4442345 | 0.80 | HTR2C (0.56) | ALDH1A1HTR2CKDM4E | |
| SCHEMBL3436700 | 0.78 | CYP1A1 (0.51) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL3435491 | 0.77 | HSP90AA1 (0.44) | MAPTTP53ALDH1A1KDM4EPTGDR2 | |
| SCHEMBL3436689 | 0.75 | TRPM8 (0.41) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL13801365 | 0.74 | PPARD (0.74) | — | |
| SCHEMBL13801349 | 0.73 | PPARD (0.63) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL3371195 | 0.73 | ALDH1A1 (0.50) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL3077683 | 0.71 | SMN1; SMN2 (0.56) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL19936515 | 0.70 | PTGDR2 (0.47) | TP53MEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078981-A2 | PPAR-DELTA LIGANDS AND METHODS OF THEIR USE | SRI INTERNATIONAL (US) | 2009-06-25 | — | — | WO | disclosed |