Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 8/20 | 0.53 |
| ▸ | MMP3 | P08254 | 8/20 | 0.53 |
| ▸ | MMP1 | P03956 | 6/20 | 0.53 |
| ▸ | MMP7 | P09237 | 6/20 | 0.53 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103460 | 1.00 | HDAC8 (0.61) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL5196301 | 0.86 | HDAC3 (0.63) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL8728655 | 0.85 | FOLH1 (0.54) | HDAC8HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL2948787 | 0.85 | FOLH1 (0.54) | HDAC8HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL13103425 | 0.83 | CYP1A2 (0.60) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL7300579 | 0.83 | FOLH1 (0.70) | CA2 | |
| SCHEMBL5802690 | 0.83 | FOLH1 (0.56) | MMP2MMP3MMP1 | |
| SCHEMBL13103439 | 0.83 | CYP1A2 (0.63) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL27513375 | 0.82 | FOLH1 (0.68) | CA2 | |
| SCHEMBL8466382 | 0.82 | MMP2 (0.67) | HDAC8HDAC3HDAC1HDAC6MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566116-A | Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same | 基础科学研究院 | 2020-08-21 | — | — | CN | disclosed |
| US-7807720-B2 | Hydroxamic acid derivatives of 3-phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PANTHERA BIOPHARMA, LLC (US) | 2010-10-05 | — | — | US | disclosed |
| WO-2008147480-A2 | HYDROXAMIC ACID DERIVATIVES OF 3-PHENYL PROPIONIC ACIDS USEFUL AS THRAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING | PANTHERA BIOPHARNA, LLC. (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080188566-A1 | Hydroxamic acid derivatives of 3-Phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PAN THERA BIOPHARMA,LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188566-A1 | Hydroxamic acid derivatives of 3-Phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | ANTXR2, PAOX, AGXT | HDAC8 690/4885HDAC3 276/4885HDAC1 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.