Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 9/20 | 0.50 |
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 4/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948787 | 1.00 | FOLH1 (0.54) | FOLH1CYP1A2PTGESALOX5PPARG | |
| SCHEMBL2945682 | 0.95 | MMP2 (0.55) | FOLH1MMP2MMP1MMP3 | |
| SCHEMBL28211408 | 0.93 | MMP2 (0.57) | FOLH1MMP2MMP1MMP3 | |
| SCHEMBL5017227 | 0.93 | MMP2 (0.57) | FOLH1MMP2MMP1MMP3 | |
| SCHEMBL14520756 | 0.89 | HDAC3 (0.59) | FOLH1CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL5802690 | 0.88 | FOLH1 (0.56) | FOLH1CYP1A2PTGESALOX5PPARG | |
| SCHEMBL7300579 | 0.88 | FOLH1 (0.70) | FOLH1CYP1A2PTGESALOX5PPARG | |
| SCHEMBL27513375 | 0.86 | FOLH1 (0.68) | FOLH1CYP1A2PTGESALOX5PPARG | |
| SCHEMBL11624296 | 0.86 | CSNK1E (0.49) | FOLH1CYP1A2PTGESALOX5PPARG | |
| SCHEMBL13103460 | 0.85 | HDAC8 (0.61) | MMP2MMP1MMP3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751927-A4 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INST OF TECHN (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0751927-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5488131-A | Synthesis of compounds with predetermined chirality | CALIFORNIA INSTITUTE OF TECHNOLOGY | 1996-01-30 | — | — | US | disclosed |
| WO-1995025714-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-09-28 | — | — | WO | disclosed |