SCHEMBL3437142

SCHEMBL3437142

COP(=O)(OP(=O)(O)O)OP(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.53
BLM P54132 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ACHE P22303 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
BTN3A1 O00481 4/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10615801 0.94 FDPS (0.47) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL1758661 0.94 FDPS (0.53) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL7737476 0.91 FDPS (0.50) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL10601758 0.91 FDPS (0.50) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL11407406 0.91 FDPS (0.50) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL16855771 0.89 FDPS (0.43) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL15760477 0.84 FDPS (0.43) FDPSBLMTDP1ACHEALDH1A1
Ethylene Glycol SCHEMBL29066335 0.84 FDPS (0.43) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL9767572 0.80 FDPS (0.45) FDPSBLMTDP1ACHEALDH1A1
SCHEMBL28938232 0.80 FDPS (0.39) FDPSBLMTDP1ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112004942-A Analysis and diagnosis method using RNA modification 国立大学法人大阪大学 2020-11-27 CN disclosed
CN-105102534-A Resin composition and film thereof KANEKA CORP 2015-11-25 CN disclosed
CN-101675110-B Polycarbonate resin composition TEIJIN LTD 2013-04-10 CN disclosed
US-7807653-B2 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2010-10-05 US disclosed
CN-101675110-A Polycarbonate resin composition TEIJIN LTD 2010-03-17 CN disclosed
US-7598230-B2 For the treatment of viral infections, microbial infections, and proliferative disorders; contain di- or triphosphate moeity mimetics, such as those containing boron anions BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2009-10-06 US disclosed
CN-101300031-A Use of SDF-1 for the treatment and/or prevention of neurological diseases SERONO LAB (CH) 2008-11-05 CN disclosed
US-20070265224-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-15 US disclosed
US-20070259832-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-08 US disclosed
US-7285658-B2 Nucleotide mimics and their prodrugs BIOTA, INC. (US) 2007-10-23 US disclosed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 EP disclosed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 WO disclosed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US disclosed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259832-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP FDPS 145/4885BLM 1763/4885TDP1 961/4885
US-20070265224-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP FDPS 145/4885BLM 1763/4885TDP1 961/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP FDPS 145/4885BLM 1763/4885TDP1 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.