Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437790 | 0.91 | MAPK1 (0.33) | BRD4TGFBR1PRKCILMNAKDM4E | |
| SCHEMBL10015411 | 0.88 | MAPK1 (0.34) | BRD4TGFBR1PRKCILMNAKDM4E | |
| SCHEMBL10015403 | 0.88 | MAPK1 (0.34) | BRD4TGFBR1PRKCILMNAKDM4E | |
| SCHEMBL10015447 | 0.87 | MAPK1 (0.35) | BRD4TGFBR1PRKCILMNAKDM4E | |
| SCHEMBL21705108 | 0.85 | MAPK1 (0.34) | BRD4TGFBR1LMNAKDM4ECCR1 | |
| SCHEMBL15385298 | 0.84 | MAPK1 (0.33) | BRD4TGFBR1LMNAKDM4ECCR1 | |
| SCHEMBL21704897 | 0.83 | ESR1 (0.35) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL15077968 | 0.82 | KDM4E (0.50) | BRD4TGFBR1PRKCILMNAKDM4E | |
| SCHEMBL14461110 | 0.82 | HSD17B10 (0.32) | HIF1ACYP1A2MAPK1HSD17B10TSHR | |
| SCHEMBL23806048 | 0.82 | BTK (0.34) | TGFBR1HIF1AMAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448894-B1 | NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KK (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-8822043-B2 | Organic compound and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8822043-B2 | Organic compound and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20120091450-A1 | NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120091450-A1 | NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120091450-A1 | NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | TRPA1, AFF4, TYR | BRD4 451/4885TGFBR1 630/4885PRKCI 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.