SCHEMBL10015411

SCHEMBL10015411

c1ccc(-c2c3cc4c5ccccc5c5cccc(c3c(-c3ccccc3)c3c6cccc7c(-c8ccccn8)ccc(c23)c76)c54)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 1/20 0.34
HTR2C P28335 1/20 0.34
TGFBR1 P36897 3/20 0.33
PRKCI P41743 1/20 0.33
LMNA P02545 3/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
BRD4 O60885 1/20 0.32
CCR1 P32246 3/20 0.32
CCR5 P51681 3/20 0.32
CCR8 P51685 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KDM4E B2RXH2 2/20 0.32
TP53 P04637 2/20 0.32
HTT P42858 2/20 0.32
ALPL P05186 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015403 1.00 MAPK1 (0.34) MAPK1TSHRHSD17B10HTR2CTGFBR1
SCHEMBL10015447 0.94 MAPK1 (0.35) MAPK1TSHRHSD17B10HTR2CTGFBR1
SCHEMBL15385298 0.93 MAPK1 (0.33) MAPK1TSHRHSD17B10HTR2CTGFBR1
SCHEMBL14461110 0.90 HSD17B10 (0.32) MAPK1TSHRHSD17B10HTR2CHPGD
SCHEMBL3437790 0.90 MAPK1 (0.33) MAPK1TSHRHSD17B10TGFBR1PRKCI
SCHEMBL10015406 0.89 GRM5 (0.34) MAPK1TSHRHSD17B10TGFBR1GRM5
SCHEMBL10015404 0.89 TGFBR1 (0.36) MAPK1TSHRHSD17B10TGFBR1LMNA
SCHEMBL10015395 0.89 TGFBR1 (0.36) MAPK1TSHRHSD17B10TGFBR1LMNA
SCHEMBL3437781 0.88 BRD4 (0.37) MAPK1TSHRHSD17B10TGFBR1PRKCI
SCHEMBL14700541 0.88 HPGD (0.35) MAPK1TSHRHSD17B10HTR2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552252-B1 2023-01-10 US disclosed
US-20220285625-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-08 US disclosed
US-20190245152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-08-08 US disclosed
US-9315460-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9315460-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-8940413-B2 Organic compound having acenaphtho[1,2-k]benzo[e]acephenanthrene derivative, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2015-01-27 US disclosed
US-8940413-B2 Organic compound having acenaphtho[1,2-k]benzo[e]acephenanthrene derivative, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2015-01-27 US disclosed
US-20140374738-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KK (JP) 2014-12-25 US disclosed
US-20140374738-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KK (JP) 2014-12-25 US disclosed
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE, ACE2, AGTR1 MAPK1 2251/4885TSHR 2063/4885HSD17B10 474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.