Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544590 | 0.91 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8961961 | 0.85 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL4958816 | 0.84 | TDP1 (0.39) | TSHRALDH1A1TP53CYP3A4CTSK | |
| SCHEMBL8961983 | 0.84 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27813096 | 0.84 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11659507 | 0.83 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL13924332 | 0.82 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL153584 | 0.81 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8962107 | 0.80 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1507509 | 0.80 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648212-B2 | Process for preparing solutions of radiation-sensitive, free-radically polymerizable organic compounds | BASF SE (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20120016079-A1 | PROCESS FOR PREPARING SOLUTIONS OF RADIATION-SENSITIVE, FREE-RADICALLY POLYMERIZABLE ORGANIC COMPOUNDS | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
| US-7682522-B2 | optically active compound capable of being used as a chiral agent, a liquid crystal composition | CHISSO CORPORATION (JP) | 2010-03-23 | — | — | US | disclosed |
| EP-2060617-A1 | Polymerizable menthol derivative | Chisso Corporation (JP) | 2009-05-20 | — | — | EP | disclosed |
| US-20090121187-A1 | POLYMERIZABLE MENTHOL DERIVATIVE | CHISSO CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| US-7264749-B2 | Alkyne compounds | BASF AKTIENGESELLSCHAFT (DE) | 2007-09-04 | — | — | US | disclosed |
| US-20050151118-A1 | Polymerizable liquid-crystalline compositions for producing films or pigments, optical components, printed or coated substrates, broadband reflective elements in electrooptical applications | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | US | disclosed |
| US-6136225-A | USED IN OPTICAL DISPLAY DEVICES AND IN CHOLESTERIC LIQUID-CRYSTALLINE COLORANTS, PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090121187-A1 | POLYMERIZABLE MENTHOL DERIVATIVE | CHRM1, CNR1, CARM1 | TSHR 2321/4885HPGD 1451/4885THRB 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.