SCHEMBL4958816

SCHEMBL4958816

CCCC(OC(=O)Cl)OC(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TSHR P16473 4/20 0.37
CYP3A4 P08684 2/20 0.37
NFKB1 P19838 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9182303 0.89 CHRM1 (0.34) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL343822 0.84 TSHR (0.39) TSHRCYP3A4CTSKALDH1A1TP53
SCHEMBL2571505 0.84 SMPD1 (0.47) TSHRALDH1A1FAAHLMNACA1
SCHEMBL8599674 0.83 CA12 (0.41) TDP1CHRM1SLC6A3TSHRCYP3A4
SCHEMBL637831 0.80 ALDH1A1 (0.35) CHRM1CHRM3ADRA1ACTSKALDH1A1
SCHEMBL10700590 0.80 CTSK (0.46) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL4958364 0.79 TSHR (0.33) TSHRALDH1A1TP53
SCHEMBL638840 0.78
SCHEMBL7360956 0.78
SCHEMBL29602658 0.77 HDAC1 (0.46) TDP1CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438368-B1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2008-02-20 EP claimed
US-6998072-B2 Containing polymerizable material and photochromic compound; ophthalmic lenses TRANSITIONS OPTICAL, INC. (US) 2006-02-14 US claimed
US-6916537-B2 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL INC. (US) 2005-07-12 US claimed
EP-1451256-B1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL INC (US) 2005-06-29 EP claimed
US-20030143404-A1 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL LIMITED (IE) 2003-07-31 US claimed
US-20030136948-A1 Photochromic polymerizable compositions TRANSITIONS OPTICAL LIMITED (IE) 2003-07-24 US claimed
US-20020009599-A1 Photochromic polyurethane coating and articles having such a coating PPG INDUSTRIES OHIO, INC. 2002-01-24 US claimed
US-5281743-A Uncatalyzed synthesis of symmetrical dicarbonates AKZO N.V. (NL) 1994-01-25 US claimed
US-20250302759-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US disclosed
WO-2025207732-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 WO disclosed
US-11952492-B2 Biodegradable, controlled release microcapsules ENCAPSYS, LLC (US) 2024-04-09 US disclosed
EP-4247537-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES Encapsys, LLC (US) 2023-09-27 EP disclosed
CN-116472103-A Biodegradable controlled release microcapsules 恩盖普有限公司 2023-07-21 CN disclosed
WO-2022109163-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2022-05-27 WO disclosed
US-5434202-A N-(β-carbony- and β-cyanovinyl)-2,2,6,6-tetramethyl-piperidine derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-07-18 US disclosed
US-5411931-A Thermal dye transfer receiving element with polycarbonate polyol crosslinked polymer EASTMAN KODAK COMPANY (US) 1995-05-02 US disclosed
EP-0585604-A2 Thermal dye transfer receiving element EASTMAN KODAK COMPANY (US) 1994-03-09 EP disclosed
US-5281743-A Uncatalyzed synthesis of symmetrical dicarbonates AKZO N.V. (NL) 1994-01-25 US disclosed
US-5266551-A Polyurethanes EASTMAN KODAK COMPANY (US) 1993-11-30 US disclosed
US-4440892-A Agents having a tumor-inhibiting action and their use BAYER AKTIENGESELLSCHAFT (DE) 1984-04-03 US disclosed