Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544590 | 0.92 | TSHR (0.45) | TSHRHPGDCHRM1AKR1A1CHRM3 | |
| SCHEMBL8961961 | 0.87 | TSHR (0.41) | TSHRHPGDCHRM1AKR1A1CHRM3 | |
| SCHEMBL27813096 | 0.85 | TSHR (0.40) | TSHRHPGDCHRM1AKR1A1CHRM3 | |
| SCHEMBL29602658 | 0.84 | HDAC1 (0.46) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13924332 | 0.84 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL343822 | 0.84 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL153584 | 0.83 | TSHR (0.41) | TSHRHPGDCHRM1AKR1A1CHRM3 | |
| SCHEMBL26093289 | 0.82 | ALDH1A1 (0.36) | TSHRHPGDSLC6A3HDAC1HDAC2 | |
| SCHEMBL8962107 | 0.81 | TSHR (0.44) | TSHRHPGDCHRM1AKR1A1CHRM3 | |
| SCHEMBL1507509 | 0.81 | TSHR (0.40) | TSHRHPGDCHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488089-A | Curable resin composition | KANSAI PAINT CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |