SCHEMBL343839

SCHEMBL343839

CC(C)(c1ccc(O)cc1)c1ccccc1C(C)(C)c1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.71
ESR2 Q92731 10/20 0.71
CYP3A4 P08684 4/20 0.71
ALDH1A1 P00352 4/20 0.71
TSHR P16473 2/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
AR P10275 1/20 0.68
SLC6A2 P23975 1/20 0.68
SLC6A4 P31645 1/20 0.68
HTR6 P50406 1/20 0.68
ESRRG P62508 1/20 0.68
SLC6A3 Q01959 1/20 0.68
LMNA P02545 2/20 0.54
TYR P14679 2/20 0.54
SHBG P04278 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
CA2 P00918 3/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3024282 0.94 ESR1 (0.63) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL177979 0.89 ESR1 (0.63) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL29446724 0.89 ESR1 (0.63) ESR1ESR2CYP3A4ALDH1A1TSHR
Phenol SCHEMBL7087181 0.88 ESR1 (0.68) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL28106853 0.87 ESR1 (0.67) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL6157236 0.86 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1TSHR
Phenol SCHEMBL9346557 0.86 ESR1 (0.64) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL21517638 0.86 ESR1 (0.59) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL4639679 0.85 ESR1 (0.60) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL2072464 0.84 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2044142-A2 POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME Medtronic, Inc. (US) 2009-04-08 EP claimed
WO-2008005371-A2 POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME MEDTRONIC, INC. (US) 2008-01-10 WO claimed
EP-1300431-B1 Process for the preparation of polyestercarbonates BAYER MATERIALSCIENCE AG (DE) 2004-12-08 EP claimed
EP-1300431-A2 Process for the preparation of polyestercarbonates Bayer Aktiengesellschaft (DE) 2003-04-09 EP claimed
US-6476179-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US claimed
JP-4368350-A None JP disclosed
JP-5310649-A None JP disclosed
JP-5320100-A None JP disclosed
JP-3066711-A None JP disclosed
WO-2025051460-A1 ELECTROMOBILITY COMPONENTS LANXESS DEUTSCHLAND GMBH (DE) 2025-03-13 WO disclosed
WO-2024101020-A1 THERMOPLASTIC RESIN COMPOSITION, SHEET, AND LAMINATE SHEET 住友化学株式会社 2024-05-16 WO disclosed
WO-2024075642-A1 POLYCARBONATE COPOLYMER AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2024-04-11 WO disclosed
EP-0331507-A1 Polyvinyl chloride plastisol composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1989-09-06 EP disclosed
EP-0106082-B1 POLYPHOSPHATES, THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1986-12-17 EP disclosed
US-4491656-A HINDERED AROMATIC DIOL COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1985-01-01 US disclosed
US-4481338-A POLYCARBONATE-POLYPHOSPHATE BLEND BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed
US-4463130-A POLYCARBONATE, STYRENE POLYMER AND POLYPHOSPHATE POLYMER; MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed
EP-0106082-A1 Polyphosphates, their preparation and their use BAYER AG (DE) 1984-04-25 EP disclosed
EP-0103230-A2 Flame-retardant polymer mixtures BAYER AG (DE) 1984-03-21 EP disclosed
US-4073746-A Mixtures of α,α'-bis-(2-hydroxy-3,5-dialkylphenyl)-p-and -m-diisopropylbenzenes, a process for the preparation thereof and the use thereof as stabilizers BAYER AKTIENGESELLSCHAFT (DT) 1978-02-14 US disclosed