SCHEMBL4639679

SCHEMBL4639679

CC(C)(c1ccc(O)cc1)c1cccc(C(C)(C)c2ccc(O)cc2)c1C(C)(C)c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.60
ESR2 Q92731 10/20 0.60
CYP3A4 P08684 3/20 0.60
TSHR P16473 2/20 0.60
AR P10275 1/20 0.60
HPGD P15428 1/20 0.60
SLC6A2 P23975 1/20 0.60
SLC6A4 P31645 1/20 0.60
HTR6 P50406 1/20 0.60
ESRRG P62508 1/20 0.60
SLC6A3 Q01959 1/20 0.60
HSD17B10 Q99714 1/20 0.60
ALDH1A1 P00352 3/20 0.57
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
CA2 P00918 1/20 0.41
SHBG P04278 1/20 0.41
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133737 0.90 ESR1 (0.54) ESR1ESR2CYP3A4TSHRAR
Propane SCHEMBL28317857 0.86 ESR1 (0.49) ESR1ESR2CYP3A4TSHRAR
SCHEMBL6157236 0.85 ESR1 (0.62) ESR1ESR2CYP3A4TSHRAR
SCHEMBL343839 0.85 ESR1 (0.71) ESR1ESR2CYP3A4TSHRAR
SCHEMBL7751060 0.81 ESR1 (0.62) ESR1ESR2CYP3A4TSHRAR
SCHEMBL29446724 0.79 ESR1 (0.63) ESR1ESR2CYP3A4TSHRAR
SCHEMBL177979 0.79 ESR1 (0.63) ESR1ESR2CYP3A4TSHRAR
SCHEMBL3024282 0.79 ESR1 (0.63) ESR1ESR2CYP3A4TSHRAR
SCHEMBL17712324 0.79 GABRA1 (0.60) ESR1ESR2CYP3A4TSHRAR
SCHEMBL18399476 0.78 ESR1 (0.45) ESR1ESR2CYP3A4TSHRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2592102-B1 BRANCHED POLYCARBONATE ASAHI CHEMICAL IND (JP) 2016-11-09 EP disclosed
EP-3004234-A1 ILLUMINATING DEVICES WITH COLOR STABLE THERMOPLASTIC LIGHT-TRANSMITTING ARTICLES SABIC Innovative Plastics IP B.V. (NL) 2016-04-13 EP disclosed
EP-2855587-A1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC Innovative Plastics IP B.V. (NL) 2015-04-08 EP disclosed
WO-2014191943-A1 ILLUMINATING DEVICES WITH COLOR STABLE THERMOPLASTIC LIGHT-TRANSMITTING ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-12-04 WO disclosed
US-8784963-B2 Branched polycarbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-07-22 US disclosed
WO-2013175455-A1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-11-28 WO disclosed
US-20130136883-A1 BRANCHED POLYCARBONATE ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-05-30 US disclosed
EP-2592102-A1 BRANCHED POLYCARBONATE Asahi Kasei Chemicals Corporation (JP) 2013-05-15 EP disclosed
EP-1954740-A1 HIGH GLASS TRANSITION TEMPERATURE COPOLYCARBONATES, METHODS OF MANUFACTURE, AND USES THEREOF General Electric Company (US) 2008-08-13 EP disclosed
WO-2007064678-A1 HIGH GLASS TRANSITION TEMPERATURE COPOLYCARBONATES, METHODS OF MANUFACTURE, AND USES THEREOF GENERAL ELECTRIC COMPANY (US) 2007-06-07 WO disclosed