SCHEMBL3439708

SCHEMBL3439708

CO[C@@H]1[C@@H](C)[C@H](C)[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@@H](C)C(=O)[C@]2(CO2)C[C@@H]1C

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.51
LMNA P02545 1/20 0.51
USP2 O75604 2/20 0.41
ABCB1 P08183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2619140 0.93 CYP3A4 (0.55) CYP3A4LMNAUSP2ABCB1
SCHEMBL3290903 0.85 CYP3A4 (0.47) CYP3A4LMNAUSP2ABCB1
SCHEMBL18120624 0.84 CYP3A4 (0.47) CYP3A4LMNAUSP2ABCB1
SCHEMBL5551907 0.78 CYP3A4 (0.74) CYP3A4LMNAUSP2ABCB1
SCHEMBL14080769 0.74 CYP3A4 (0.51) CYP3A4LMNAUSP2ABCB1
SCHEMBL14081013 0.71 CYP3A4 (0.48) CYP3A4LMNAUSP2ABCB1
SCHEMBL14050104 0.67 MEN1 (0.33) LMNA
SCHEMBL13120128 0.67 MEN1 (0.33) LMNA
SCHEMBL13105399 0.67 MEN1 (0.33) LMNA
SCHEMBL13105444 0.67 MEN1 (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130266556-A9 PROCESSING BIOMASS XYLECO, INC. (US) 2013-10-10 US disclosed
US-20130164818-A9 PROCESSING BIOMASS XYLECO, INC. (US) 2013-06-27 US disclosed
US-20120094358-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2012-04-19 US disclosed
US-20110081336-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2011-04-07 US disclosed
US-20100124583-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110081336-A1 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 CYP3A4 1414/4885LMNA 2646/4885USP2 1477/4885
US-20130266556-A9 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 CYP3A4 1414/4885LMNA 2646/4885USP2 1477/4885
US-20100124583-A1 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 CYP3A4 1414/4885LMNA 2646/4885USP2 1477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.