Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031372 | 0.98 | TSHR (0.44) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL285648 | 0.98 | TSHR (0.44) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL712581 | 0.98 | TSHR (0.44) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL183807 | 0.95 | TSHR (0.42) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL5968073 | 0.92 | TSHR (0.40) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL1132225 | 0.88 | TSHR (0.44) | TSHRUSP2MAPTGAATHRB | |
| SCHEMBL246414 | 0.88 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL26362898 | 0.88 | TSHR (0.42) | TSHRUSP2MAPTTHRBALDH1A1 | |
| SCHEMBL26362902 | 0.88 | TSHR (0.42) | TSHRUSP2MAPTTHRBALDH1A1 | |
| Fluoride SCHEMBL28103175 | 0.87 | TSHR (0.43) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033125-B1 | Relining material for dentures | KURARAY CO (JP) | 2003-09-24 | — | — | EP | claimed |
| US-6410612-B1 | ACRYLIC POLYMER BLEND | KURARAY CO., LTD. (JP) | 2002-06-25 | — | — | US | claimed |
| EP-1033125-A1 | Relining material for dentures | KURARAY CO., LTD. (JP) | 2000-09-06 | — | — | EP | claimed |
| EP-2163234-B1 | DENTAL FILLING/RESTORATION KIT | TOKUYAMA DENTAL CORP (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-8506298-B2 | Dental filling/restoration kit | TOKUYAMA DENTAL CORPORATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20100216096-A1 | DENTAL FILLING/RESTORATION KIT | TOKUYAMA DENTAL CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2163234-A1 | DENTAL FILLING/RESTORATION KIT | Tokuyama Dental Corporation (JP) | 2010-03-17 | — | — | EP | disclosed |
| EP-1033125-B1 | Relining material for dentures | KURARAY CO (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6410612-B1 | ACRYLIC POLYMER BLEND | KURARAY CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1033125-A1 | Relining material for dentures | KURARAY CO., LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |