SCHEMBL2031372

SCHEMBL2031372

C=C(C)C(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
USP2 O75604 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
RECQL P46063 1/20 0.36
GAA P10253 1/20 0.35
THRB P10828 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285648 1.00 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL712581 1.00 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL3440177 0.98 TSHR (0.42) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL183807 0.94 TSHR (0.42) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL5968073 0.91 TSHR (0.40) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL26362898 0.89 TSHR (0.42) TSHRUSP2MAPTTHRBALDH1A1
SCHEMBL26362902 0.89 TSHR (0.42) TSHRUSP2MAPTTHRBALDH1A1
SCHEMBL248380 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL246497 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL246347 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240384131-A1 MULTIFUNCTIONAL MODIFIED SILANE COMPOUND AND MANUFACTURE METHOD THEREOF, HARDENED COATING LAYER AND MANUFACTURE METHOD THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-11-21 US claimed
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
EP-3520861-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR Living Proof, Inc. (US) 2019-08-07 EP claimed
EP-2205196-B1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2018-12-26 EP claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2017-11-30 US claimed
US-9770399-B2 Hair care compositions and methods of treating hair LIVING PROOF, INC. (US) 2017-09-26 US claimed
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2013-12-19 US claimed
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2010-11-04 US claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
EP-3688046-B1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC (US) 2026-01-07 EP disclosed
WO-2025043220-A1 FLUID CONDUITS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-27 WO disclosed
US-20240384131-A1 MULTIFUNCTIONAL MODIFIED SILANE COMPOUND AND MANUFACTURE METHOD THEREOF, HARDENED COATING LAYER AND MANUFACTURE METHOD THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-11-21 US disclosed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
EP-0890131-B1 PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ELSICON INC INC IN DELAWARE US (US) 2002-09-11 EP disclosed
US-5929201-A A POLYAMIC ACID IS THE REACTION PRODUCT OF A FLUORINATED MONOAMINE, A DIAMINE AND ATLEAST ONE TETERACARBOXYLIC DIANHYDRIDE ELSICON, INC. (US) 1999-07-27 US disclosed
US-5856431-A POLYIMIDE ALLIANT TECHSYSTEMS INC. (US) 1999-01-05 US disclosed
US-5817743-A ANISOTROPICALLY ABSORBING MOLECULES, POLARIZED LIGHT ALLIANT TECHSYSTEMS INC. (US) 1998-10-06 US disclosed
US-5731405-A POLYIMIDE COPOLYMER MADE FROM DIARYL KETONE TETRACARBOXYLIC DIANHYDRIDE, HYDROPHOBIC DIAMINE, AND ALICYCLIC TETRACARBOXYLIC ANHYDRIDE REACTANTS ALLIANT TECHSYSTEMS INC. (US) 1998-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TSHR 1808/4885USP2 2079/4885MAPT 1257/4885
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TSHR 1808/4885USP2 2079/4885MAPT 1257/4885
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TSHR 1808/4885USP2 2079/4885MAPT 1257/4885
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 TSHR 3749/4885USP2 1259/4885MAPT 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.