SCHEMBL712581

SCHEMBL712581

C=C(C)C(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
USP2 O75604 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
RECQL P46063 1/20 0.36
GAA P10253 1/20 0.35
THRB P10828 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285648 1.00 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL2031372 1.00 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL3440177 0.98 TSHR (0.42) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL183807 0.94 TSHR (0.42) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL5968073 0.91 TSHR (0.40) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL26362898 0.89 TSHR (0.42) TSHRUSP2MAPTTHRBALDH1A1
SCHEMBL26362902 0.89 TSHR (0.42) TSHRUSP2MAPTTHRBALDH1A1
SCHEMBL248380 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL246497 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL246347 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-20160369103-A1 LOW REFRACTIVE INDEX COATING FOR OPTICAL FIBERS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME OFS FITEL LLC (US) 2016-12-22 US claimed
EP-3688046-B1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC (US) 2026-01-07 EP disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
WO-2025043220-A1 FLUID CONDUITS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-27 WO disclosed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
EP-2872572-B1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES HARVARD COLLEGE (US) 2024-06-19 EP disclosed
WO-2024086390-A2 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-25 WO disclosed
US-11945890-B2 Fluorinated PVC copolymer compositions for increased ultraviolet protection Mexichem Specialty Resins Inc. (US) 2024-04-02 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
EP-0583918-A2 Reflection preventing film and process for forming resist pattern using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-02-23 EP disclosed
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed
US-5252395-A Containing an acrylic ester copolymer LINTEC CORPORATION (JP) 1993-10-12 US disclosed
US-5235013-A Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester CIBA-GEIGY CORPORATION 1993-08-10 US disclosed
EP-0491169-A2 A blister resistant pressure sensitive adhesive sheet LINTEC Corporation (JP) 1992-06-24 EP disclosed
US-4794145-A REACTING WITH ALKYL SUBSTITUTED STYRENE, THEN MONOMER THE DOW CHEMICAL COMPANY (US) 1988-12-27 US disclosed
US-4786689-A Process for metallating nonconjugated diene-containing ethylene polymers and graft polymers prepared therefrom THE DOW CHEMICAL COMPANY (US) 1988-11-22 US disclosed
US-4761456-A ALKYLLITHIUM, POTASSIUM ALKOXIDE, TERTIARY DIAMINE THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed