Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352052 | 1.00 | CYP1A2 (0.49) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| Hydrochloric Acid SCHEMBL3195312 | 0.98 | CYP1A2 (0.47) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| SCHEMBL29585627 | 0.89 | HTR2B (0.58) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| SCHEMBL31238892 | 0.89 | HTR2B (0.58) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| SCHEMBL24424025 | 0.89 | HTR2B (0.58) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| Hydrochloric Acid SCHEMBL5381370 | 0.87 | HTR2B (0.57) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| Hydrochloric Acid SCHEMBL8828239 | 0.87 | HTR2B (0.57) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| Hydrochloric Acid SCHEMBL30032402 | 0.87 | CYP1A2 (0.42) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| SCHEMBL2665681 | 0.86 | L3MBTL1 (0.54) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 | |
| SCHEMBL9625796 | 0.86 | L3MBTL1 (0.54) | CYP1A2ALDH1A1TSHRCHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147283-B1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY LTD (CN) | 2022-08-17 | — | — | EP | disclosed |
| US-9938272-B2 | Hydrazine compound as blood coagulation factor Xa inhibitor | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-9938272-B2 | Hydrazine compound as blood coagulation factor Xa inhibitor | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-20170152259-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20170152259-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| EP-3147283-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | North China Pharmaceutical Company., Ltd. (CN) | 2017-03-29 | — | — | EP | disclosed |
| EP-3147283-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | North China Pharmaceutical Company., Ltd. (CN) | 2017-03-29 | — | — | EP | disclosed |
| US-9533979-B2 | Amino-derivatives as novel inhibitors of histone deacetylase | JANSSEN PHARMACEUTICA NV (BE) | 2017-01-03 | — | — | US | disclosed |
| WO-2015176625-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | 南京明德新药研发股份有限公司 | 2015-11-26 | — | — | WO | disclosed |
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |
| WO-2008022945-A1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |
| US-20050119250-A1 | Antiproliferative agents | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-06-02 | — | — | US | disclosed |
| EP-1485370-A1 | AMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003076430-A1 | AMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-09-18 | — | — | WO | disclosed |
| EP-0327800-B1 | 6-PHENYLDIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | HEUMANN PHARMA GMBH & CO (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-5108998-A | CARDIOTONIC THIADIAZINE DERIVATIVES | HEUMANN PHARMA GMBH & CO. (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0399196-A1 | Diazine derivatives, process for their preparation, and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1990-11-28 | — | — | EP | disclosed |
| US-4954501-A | INOTROPIC AGENTS | HEUMANN PHARMA GMBH & CO. (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0327800-A2 | 6-Phenyldihydro-3(2H)-pyridazinones, process for their preparation and medicines containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1989-08-16 | — | — | EP | disclosed |
| US-4291042-A | ANTIINFLAMMATORY AGENTS, ANTICONVULSANTS, ANTIARRHYTHMIA AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152259-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | F12, F10, F11 | CYP1A2 553/4885ALDH1A1 2302/4885TSHR 1331/4885 |
| US-20050119250-A1 | Antiproliferative agents | HDAC1, HDAC11, MKI67 | CYP1A2 3694/4885ALDH1A1 1033/4885TSHR 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.