SCHEMBL344079

SCHEMBL344079

C=CC(=O)Oc1ccc(CCN)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.70
TAAR1 Q96RJ0 2/20 0.48
MAOB P27338 4/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTR3A P46098 1/20 0.44
BACE1 P56817 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17791334 0.89 THRB (0.79) THRBALDH1A1
SCHEMBL13888390 0.85 THRB (0.64) THRBMAOB
SCHEMBL242424 0.85 THRB (0.78) THRBKMT2A
SCHEMBL24517163 0.84 THRB (0.81) THRBALDH1A1KMT2A
SCHEMBL22566602 0.84 THRB (0.72) THRBMAOBKMT2A
SCHEMBL22566502 0.84 THRB (0.72) THRBMAOBKMT2A
SCHEMBL342562 0.84 THRB (0.72) THRBTDP1
SCHEMBL4596017 0.82 THRB (1.00) THRBALDH1A1L3MBTL1KMT2A
SCHEMBL18566936 0.82 THRB (0.70) THRBKDM4EKMT2A
SCHEMBL17791344 0.82 THRB (0.70) THRBKDM4ESLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302011-B1 Curable gel inks with reduced syneresis and halo formation XEROX CORP (US) 2014-07-09 EP claimed
US-20080004402-A1 Polymeric product for film formation BORBELY JANOS 2008-01-03 US claimed
EP-1201720-B1 Printing fluid additives promoting overcoat adhesion HEWLETT PACKARD CO (US) 2004-09-15 EP claimed
US-6610412-B2 Clear protective thermal transfer overcoating and acrylic polymer compatibilizer; computer prints HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-08-26 US claimed
US-20030119973-A1 Printing fluid additives promoting overcoat adhesion HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-06-26 US claimed
US-6417249-B1 INK JET PRINTING INK FOR COLOR VEHICLES, CORE/SHELL BINDERS, SMUDGE PROOF HEWLETT-PACKARD COMPANY 2002-07-09 US claimed
EP-1201720-A1 Printing fluid additives promoting overcoat adhesion Hewlett-Packard Company (US) 2002-05-02 EP claimed
US-6248805-B1 THERMAL INK JET PRNTING HEWLETT-PACKARD COMPANY 2001-06-19 US claimed
US-6057384-A VEHICLE AND COLORANT ASSOCIATED WITH A PRIMER CORE/SHELL POLYMER; DURABLR SMEAR-FAST FILM HEWLETT-PACKARD COMPANY (US) 2000-05-02 US claimed
US-5990202-A DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY HEWLETT-PACKARD COMPANY (US) 1999-11-23 US claimed
EP-2302011-B1 Curable gel inks with reduced syneresis and halo formation XEROX CORP (US) 2014-07-09 EP disclosed
US-8449095-B2 Radiation curable solid ink compositions suitable for transfuse printing applications XEROX CORPORATION (US) 2013-05-28 US disclosed
US-8262210-B2 Curable gel inks with reduced syneresis and halo formation XEROX CORPORATION (US) 2012-09-11 US disclosed
US-20120013690-A1 RADIATION CURABLE SOLID INK COMPOSITIONS SUITABLE FOR TRANSFUSE PRINTING APPLICATIONS XEROX CORPORATION (US) 2012-01-19 US disclosed
EP-1027392-B1 LATEX POLYMER BLENDS FOR INK-JET INKS HEWLETT PACKARD CO (US) 2011-04-06 EP disclosed
US-5990202-A DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY HEWLETT-PACKARD COMPANY (US) 1999-11-23 US disclosed
WO-1999023181-A1 INK-JET INK COMPOSITIONS HAVING MAGNETIC PROPERTIES HEWLETT-PACKARD COMPANY (US) 1999-05-14 WO disclosed
WO-1999023182-A1 LATEX POLYMER BLENDS FOR INK-JET INKS HEWLETT-PACKARD COMPANY (US) 1999-05-14 WO disclosed
WO-1999023183-A1 PRINTING INK COMPOSITIONS HAVING SUPERIOR SMEAR-FASTNESS HEWLETT-PACKARD COMPANY (US) 1999-05-14 WO disclosed
WO-1999023126-A1 DURABLE, FILM-FORMING, WATER-DISPERSIVE POLYMERS HEWLETT-PACKARD COMPANY (US) 1999-05-14 WO disclosed