SCHEMBL3441239

SCHEMBL3441239

NC(=O)CC(NCCO)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 4/20 0.38
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
ITGB2 P05107 1/20 0.30
ICAM1 P05362 1/20 0.30
ITGAL P20701 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1221420 1.00 ECE1 (0.38) ECE1MEN1USP2ALDH1A1MAPT
SCHEMBL8364638 0.88 ECE1 (0.34) ECE1
SCHEMBL1374076 0.88 ECE1 (0.36) ECE1
SCHEMBL1374080 0.88 ECE1 (0.36) ECE1
SCHEMBL1226547 0.85 ECE1 (0.41) ECE1MEN1ALDH1A1MAPTKMT2A
SCHEMBL1226550 0.85 ECE1 (0.41) ECE1MEN1ALDH1A1MAPTKMT2A
SCHEMBL5144359 0.85 GABRR1 (0.32) MEN1USP2ALDH1A1MAPTKMT2A
SCHEMBL4030392 0.85 GABRR1 (0.32) MEN1USP2ALDH1A1MAPTKMT2A
SCHEMBL4553554 0.85 GABRR1 (0.32) MEN1USP2ALDH1A1MAPTKMT2A
SCHEMBL3229885 0.84 TDP1 (0.36) ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4545964-A2 CHROMATOGRAPHIC ISOLATION OF CELLS AND OTHER COMPLEX BIOLOGICAL MATERIALS Juno Therapeutics GmbH (DE) 2025-04-30 EP claimed
WO-2025083196-A1 A METHOD OF MANUFACTURING A CELLULAR THERAPY PRODUCT AND RESPECTIVE KITS AND DEVICES TQ THERAPEUTICS GMBH (DE) 2025-04-24 WO claimed
US-20250020556-A1 CHROMATOGRAPHIC ISOLATION OF CELLS AND OTHER COMPLEX BIOLOGICAL MATERIALS JUNO THERAPEUTICS GMBH (DE) 2025-01-16 US claimed
EP-2817625-B1 CHROMATOGRAPHIC ISOLATION OF CELLS AND OTHER COMPLEX BIOLOGICAL MATERIALS JUNO THERAPEUTICS GMBH (DE) 2025-01-01 EP claimed
US-20230173080-A1 COMPOSITION OF IMMUNOMODULATING SERPIN, SERP-1 SERPASS BIOLOGICS, INC. 2023-06-08 US claimed
EP-4143222-A2 COMPOSITION OF IMMUNOMODULATING SERPIN, SERP-1 Arizona Board of Regents on behalf of Arizona State University (US) 2023-03-08 EP claimed
US-20220275041-A1 MODIFIED IFNL3 POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING MOIETY AND THEIR USES EXALT THERAPEUTICS, LLC 2022-09-01 US claimed
US-20220056083-A1 STREPTAVIDIN MUTEINS AND METHODS OF USING THEM IBA LIFESCIENCES GMBH (GI) 2022-02-24 US claimed
CN-103083681-A Drug for treating tumors and application thereof UNIV TSINGHUA 2013-05-08 CN claimed
CN-101596320-A A kind of medicine and application thereof for the treatment of tumor UNIV TSINGHUA (CN) 2009-12-09 CN claimed
CN-101405019-A Medicine for treating tumor and application thereof UNIV TSINGHUA (CN) 2009-04-08 CN claimed
CN-101002946-A Medicine for treating tumor and application thereof UNIV TSINGHUA (CN) 2007-07-25 CN claimed
EP-0788375-A3 OFFORD ROBIN EWART 1997-09-17 EP claimed
EP-0788375-A2 FUNCTIONALIZED POLYMERS FOR SITE-SPECIFIC ATTACHMENT Offord, Robin Ewart (CH) 1997-08-13 EP claimed
WO-1996041813-A9 FUNCTIONALIZED POLYMERS FOR SITE-SPECIFIC ATTACHMENT 1997-06-19 WO claimed
WO-1996041813-A2 FUNCTIONALIZED POLYMERS FOR SITE-SPECIFIC ATTACHMENT OFFORD ROBIN E (CH) 1996-12-27 WO claimed
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives AMBRX, INC. (US) 2026-05-12 US disclosed
EP-4104853-B1 ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT POLARIS GROUP (KY) 2026-05-06 EP disclosed
EP-0685504-A2 Polyaspartic acid derivatives and process for preparing the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-12-06 EP disclosed
EP-0539167-A2 Peg imidates and protein derivatives thereof ORTHO PHARMACEUTICAL CORPORATION (US) 1993-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275041-A1 MODIFIED IFNL3 POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING MOIETY AND THEIR USES IFNG, IRF3, IFNAR1 ECE1 2267/4885MEN1 2902/4885USP2 2058/4885
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives DDOST, DMPK, KRTCAP2 ECE1 2096/4885MEN1 4217/4885USP2 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.