Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGAV | P06756 | 3/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144359 | 1.00 | GABRR1 (0.32) | GABRR1LMNASLC22A6CA2CA4 | |
| SCHEMBL4553554 | 1.00 | GABRR1 (0.32) | GABRR1LMNASLC22A6CA2CA4 | |
| Aspartic Acid SCHEMBL7744939 | 0.89 | GRIK1 (0.35) | KMT2A | |
| SCHEMBL8364636 | 0.89 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL1880686 | 0.88 | CAMK2A (0.33) | GABRR1LMNAALDH1A1ITGB3ITGAV | |
| SCHEMBL8424379 | 0.88 | CAMK2A (0.33) | GABRR1LMNAALDH1A1ITGB3ITGAV | |
| SCHEMBL28308288 | 0.86 | GPR84 (0.34) | TDP1 | |
| Phenol SCHEMBL29187478 | 0.85 | ALDH1A1 (0.38) | LMNACA2CA4ALDH1A1MAPT | |
| SCHEMBL3441239 | 0.85 | ECE1 (0.38) | MEN1USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL1221420 | 0.85 | ECE1 (0.38) | MEN1USP2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070166383-A1 | Anionic hydrogel matrices with ph dependent modified release as drug carriers | SIGMA-TAU INDUSTIRE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-19 | — | — | US | claimed |
| EP-1729732-A1 | ANIONIC HYRDOGEL MATRICES WITH PH DEPENDENT MODIFIED RELEASE AS DRUG CARRIERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2006-12-13 | — | — | EP | claimed |
| WO-2005094792-A1 | ANIONIC HYDROGEL MATRICES WITH PH DEPENDENT MODIFIED RELEASE AS DRUG CARRIERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-10-13 | — | — | WO | claimed |
| EP-1729732-B1 | ANIONIC HYDROGEL MATRICES WITH PH DEPENDENT MODIFIED RELEASE AS DRUG CARRIERS | SIGMA TAU IND FARMACEUTI (IT) | 2009-04-15 | — | — | EP | disclosed |
| US-20070166383-A1 | Anionic hydrogel matrices with ph dependent modified release as drug carriers | SIGMA-TAU INDUSTIRE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-19 | — | — | US | disclosed |
| EP-1729732-A1 | ANIONIC HYRDOGEL MATRICES WITH PH DEPENDENT MODIFIED RELEASE AS DRUG CARRIERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005094792-A1 | ANIONIC HYDROGEL MATRICES WITH PH DEPENDENT MODIFIED RELEASE AS DRUG CARRIERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-10-13 | — | — | WO | disclosed |