SCHEMBL34433397

SCHEMBL34433397

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nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 1/20 0.47
▸ PTGS1 P23219 1/20 0.45
▸ GSTK1 Q9Y2Q3 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ THPO P40225 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ BLM P54132 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NOD1 Q9Y239 1/20 0.39
▸ OPRM1 P35372 3/20 0.37
▸ OPRD1 P41143 3/20 0.37
▸ OPRK1 P41145 1/20 0.37
▸ MME P08473 6/20 0.36
▸ PAX8 Q06710 1/20 0.35
▸ NMT2 O60551 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30671950 0.92 ACE (0.49) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL29447806 0.89 MME (0.44) PTGS1GSTK1NOD1OPRM1OPRD1
SCHEMBL29516761 0.86 ACE (0.53) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL29373113 0.86 ACE (0.53) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL34433398 0.85 PTGS1 (0.45) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL29461574 0.85 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30063535 0.84 ACE (0.46) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL29473500 0.83 ACE (0.43) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL29532503 0.83 PTGS1 (0.45) ACEPTGS1GSTK1KDM4EMAPT
SCHEMBL30484374 0.82 PTGS1 (0.47) ACEPTGS1GSTK1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595286-B2 Fucose-binding protein, method for producing same, and use of same TOSOH CORPORATION (JP) 2026-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595286-B2 Fucose-binding protein, method for producing same, and use of same FUBP1, MRPL21, GLMN ACE 3670/4885PTGS1 2962/4885GSTK1 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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