Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373113 | 1.00 | ACE (0.53) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL30671950 | 0.92 | ACE (0.49) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL31456588 | 0.88 | ACE (0.50) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL34433397 | 0.86 | ACE (0.47) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL1493227 | 0.85 | PTGS1 (0.55) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL29351781 | 0.85 | MME (0.47) | PTGS1GSTK1TERTNOD1OPRD1 | |
| SCHEMBL29815598 | 0.85 | PTGS1 (0.49) | ACEPTGS1GSTK1MAPTPTGS2 | |
| SCHEMBL29496724 | 0.84 | CA2 (0.46) | PTGS1GSTK1TERTNOD1ENPEP | |
| SCHEMBL29590916 | 0.84 | ALDH1A1 (0.51) | MAPTTERTFOLH1OPRD1OPRM1 | |
| SCHEMBL2544386 | 0.83 | ACE (0.69) | ACEPTGS1MAPTPTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12616761-B2 | CXCR4-targeting compounds | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-05-05 | — | — | US | claimed |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-10-17 | — | — | US | claimed |
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-03-28 | — | — | US | claimed |
| EP-4232459-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | Provincial Health Services Authority (CA) | 2023-08-30 | — | — | EP | claimed |
| CN-116457028-A | Novel CXCR4 targeting compounds | 省卫生服务机构 | 2023-07-18 | — | — | CN | claimed |
| WO-2022082312-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-04-28 | — | — | WO | claimed |
| US-12616761-B2 | CXCR4-targeting compounds | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-05-05 | — | — | US | disclosed |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-10-17 | — | — | US | disclosed |
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240100203-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | CXCR4, CXCL12, CXCR2 | ACE 3897/4885PTGS1 3437/4885GSTK1 3873/4885 |
| US-20240342321-A1 | NOVEL CXCR4-TARGETING COMPOUNDS | CXCR4, CXCL12, CXCR2 | ACE 3897/4885PTGS1 3437/4885GSTK1 3873/4885 |
| US-12616761-B2 | CXCR4-targeting compounds | CXCR4, CXCR2, CXCR3 | ACE 4450/4885PTGS1 3599/4885GSTK1 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.