Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 6/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34433397 | 0.92 | ACE (0.47) | ACEPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL29373113 | 0.92 | ACE (0.53) | ACEPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL29516761 | 0.92 | ACE (0.53) | ACEPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL30063535 | 0.88 | ACE (0.46) | ACEPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL29351781 | 0.87 | MME (0.47) | PTGS1GSTK1OPRM1OPRD1NOD1 | |
| SCHEMBL29461574 | 0.87 | ACE (0.59) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL29447806 | 0.86 | MME (0.44) | PTGS1GSTK1OPRM1OPRD1NOD1 | |
| SCHEMBL29532503 | 0.85 | PTGS1 (0.45) | ACEPTGS1GSTK1KDM4EMAPT | |
| SCHEMBL29350589 | 0.84 | NOD1 (0.47) | PTGS1GSTK1NOD1MMENMT2 | |
| SCHEMBL30463399 | 0.84 | PTGS1 (0.50) | ACEPTGS1GSTK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051794-A1 | RADIONUCLIDE-DRUG CONJUGATE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 同宜医药（苏州）有限公司 | 2024-03-14 | — | — | WO | claimed |
| WO-2023202654-A1 | COMPOUND AND USE THEREOF | 同宜医药（苏州）有限公司 | 2023-10-26 | — | — | WO | disclosed |