SCHEMBL3445210

SCHEMBL3445210

c1ccc(-c2nnc(-c3ccccc3)c(-c3ccccc3)n2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.81
ALDH1A1 P00352 6/20 0.78
MAPT P10636 4/20 0.78
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
ADORA2A P29274 2/20 0.59
ADORA1 P30542 2/20 0.59
MAPK1 P28482 1/20 0.59
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
GAA P10253 2/20 0.57
LMNA P02545 2/20 0.55
NPSR1 Q6W5P4 4/20 0.54
TDP1 Q9NUW8 1/20 0.54
USP2 O75604 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2849974 0.98 ALDH1A1 (0.81) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL29556760 0.98 ALDH1A1 (0.81) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL32668864 0.98 ALDH1A1 (0.81) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL13108734 0.96 ALDH1A1 (0.79) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5590226 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5592678 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5590317 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5589974 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5590751 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL5590302 0.90 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816520-B2 Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-10-19 US claimed
US-10991980-B2 Electrolytic solution for secondary battery, secondary battery, battery pack, electrically-driven vehicle, electric power storage system, electrically-driven tool, and electronic device MURATA MANUFACTURING CO., LTD. (JP) 2021-04-27 US disclosed
US-20190267672-A1 ELECTROLYTIC SOLUTION FOR SECONDARY BATTERY, SECONDARY BATTERY, BATTERY PACK, ELECTRICALLY-DRIVEN VEHICLE, ELECTRIC POWER STORAGE SYSTEM, ELECTRICALLY-DRIVEN TOOL, AND ELECTRONIC DEVICE MURATA MANUFACTURING CO., LTD. (JP) 2019-08-29 US disclosed
CN-102229576-B Method for synthesizing 1,2,4-triazine compound by using micro-reactor FUDAN UNIVERSITY (CN) 2014-10-29 CN disclosed
CN-102229576-A Method for synthesizing 1,2,4-triazine compound by using micro-reactor UNIV FUDAN 2011-11-02 CN disclosed
CN-100517814-C Anode active material, producing method thereof and lithium battery using the same SAMSUNG SDI CO LTD (KR) 2009-07-22 CN disclosed
CN-1913201-A Anode active material, producing method thereof and lithium battery using the same SAMSUNG SDI CO LTD (KR) 2007-02-14 CN disclosed
US-20070020519-A1 Anode active material, manufacturing method thereof and lithium battery using the anode active material SAMSUNG SDI CO., LTD. (KR) 2007-01-25 US disclosed
EP-0925319-B1 TRIAZINE POLYMERS AND THE APPLICATION THEREOF IN ELECTROLUMINESCENT ARRANGEMENTS BAYER AG (DE) 2001-12-05 EP disclosed