SCHEMBL2849974

SCHEMBL2849974

c1ccc(-c2nnc(-c3ccc(-c4nnc(-c5ccccc5)c(-c5ccccc5)n4)cc3)nc2-c2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.81
MAPT P10636 4/20 0.81
SMN1; SMN2 Q16637 4/20 0.78
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
ADORA2A P29274 2/20 0.57
ADORA1 P30542 2/20 0.57
MAPK1 P28482 1/20 0.56
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
GAA P10253 2/20 0.56
LMNA P02545 3/20 0.53
NPSR1 Q6W5P4 5/20 0.53
TDP1 Q9NUW8 1/20 0.53
USP2 O75604 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32668864 1.00 ALDH1A1 (0.81) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL29556760 1.00 ALDH1A1 (0.81) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL13108734 0.98 ALDH1A1 (0.79) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL3445210 0.98 SMN1; SMN2 (0.81) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL24715264 0.90 MAPT (0.69) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL28323966 0.90 ALDH1A1 (0.69) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL11772051 0.90 ALDH1A1 (0.69) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL1306085 0.90 MAPT (1.00) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL20387001 0.90 ALDH1A1 (1.00) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL21937008 0.89 MAPT (0.67) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083654-A1 PHOTOPROTECTIVE SYSTEM CONSISTING OF 4 SUNSCREENS PIERRE FABRE DERMO-COSMETIQUE (FR) 2026-03-26 US claimed
EP-4518831-A1 USE OF PHENYLENE BIS-DIPHENYLTRIAZINE FOR PRESERVING IMMUNE DEFENSES OF THE SKIN Pierre Fabre Dermo-Cosmétique (FR) 2025-03-12 EP claimed
WO-2025021858-A1 5,6,5',6'-TETRAPHENYL-3,3'-(1,4-PHENYLENE)-BIS[1,2,4] TRIAZINE FOR THE TREATMENT AND/OR PREVENTION OF A PRE-CANCEROUS OR CANCEROUS SKIN LESION PIERRE FABRE DERMO-COSMETIQUE (FR) 2025-01-30 WO claimed
EP-4486294-A1 USE OF PHENYLENE BIS-DIPHENYLTRIAZINE FOR PROTECTING THE SKIN BARRIER FUNCTION AND THE SKIN MICROBIOTA Pierre Fabre Dermo-Cosmétique (FR) 2025-01-08 EP claimed
US-20230398048-A1 NOVEL SYSTEM FOR SOLUBILISING FAT-SOLUBLE ORGANIC SUN FILTERS PIERRE FABRE DERMO-COSMETIQUE (FR) 2023-12-14 US claimed
WO-2023214065-A1 USE OF PHENYLENE BIS-DIPHENYLTRIAZINE FOR PRESERVING IMMUNE DEFENSES OF THE SKIN PIERRE FABRE DERMO-COSMETIQUE (FR) 2023-11-09 WO claimed
US-11793742-B2 Mixtures of cosmetic UV absorbers BASF SE (DE) 2023-10-24 US claimed
WO-2023166268-A1 USE OF PHENYLENE BIS-DIPHENYLTRIAZINE FOR PROTECTING THE SKIN BARRIER FUNCTION AND THE SKIN MICROBIOTA PIERRE FABRE DERMO-COSMETIQUE (FR) 2023-09-07 WO claimed
CN-116685301-A Novel system for dissolving fat-soluble organic solar filters 皮埃尔·法布尔皮肤化妆品公司 2023-09-01 CN claimed
US-11723850-B2 Liquid and transparent blend of UV filters Symrise, AG (DE) 2023-08-15 US claimed
EP-3191075-A1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2017-07-19 EP claimed
EP-3128993-A1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2017-02-15 EP claimed
US-20170027835-A1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2017-02-02 US claimed
WO-2016037942-A1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2016-03-17 WO claimed
WO-2015155158-A1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2015-10-15 WO claimed
US-7816520-B2 Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-10-19 US claimed
EP-1753747-B1 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS FABRE PIERRE DERMO COSMETIQUE (FR) 2010-01-13 EP claimed
US-20080267892-A1 Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-10-30 US claimed
EP-1753747-A1 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS Pierre Fabre Dermo-Cosmetique (FR) 2007-02-21 EP claimed
WO-2005121128-A1 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS PIERRE FABRE DERMO-COSMETIQUE (FR) 2005-12-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083654-A1 PHOTOPROTECTIVE SYSTEM CONSISTING OF 4 SUNSCREENS MITF, TYR, ERCC5 ALDH1A1 78/4885MAPT 2955/4885SMN1; SMN2 4073/4885
US-11723850-B2 Liquid and transparent blend of UV filters F2, F12, F10 ALDH1A1 594/4885MAPT 1591/4885SMN1; SMN2 4515/4885
US-20170027835-A1 MIXTURES OF COSMETIC UV ABSORBERS BTD, TMSB10, TYR ALDH1A1 771/4885MAPT 2636/4885SMN1; SMN2 4220/4885
US-11793742-B2 Mixtures of cosmetic UV absorbers BTD, TMSB10, TH ALDH1A1 734/4885MAPT 2781/4885SMN1; SMN2 4421/4885
US-20080267892-A1 Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair TYR, H1-0, TELO2 ALDH1A1 785/4885MAPT 4276/4885SMN1; SMN2 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.