Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649261 | 0.87 | KDM4E (0.42) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL31629442 | 0.87 | KDM4E (0.42) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL3445568 | 0.86 | KDM4E (0.38) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL31649287 | 0.83 | CSNK1D (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL13046297 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL31629507 | 0.81 | KDM4E (0.43) | MAPTALDH1A1KDM4EHPGDGABRP | |
| SCHEMBL12254659 | 0.81 | KDM4E (0.43) | MAPTALDH1A1KDM4EHPGDGABRP | |
| SCHEMBL31649027 | 0.81 | KDM4E (0.43) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL31649019 | 0.81 | RXFP1 (0.43) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL31649313 | 0.81 | KDM4E (0.40) | MAPTALDH1A1SMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090291437-A1 | METHODS FOR TARGETING QUADRUPLEX SEQUENCES | CYLENE PHARMACEUTICALS, INC. | 2009-11-26 | — | — | US | disclosed |
| US-20090291437-A1 | METHODS FOR TARGETING QUADRUPLEX SEQUENCES | CYLENE PHARMACEUTICALS, INC. | 2009-11-26 | — | — | US | disclosed |
| WO-2007056113-A2 | METHODS FOR TARGETING QUADRUPLEX SEQUENCES | CYLENE PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20060074089-A1 | Quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074089-A1 | Quinolone analogs | NQO2, BAX, MCL1 | MAPT 4613/4885ALDH1A1 2050/4885SMN1; SMN2 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.