Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445304 | 0.86 | MAPT (0.42) | KDM4ELMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL13107723 | 0.81 | KDM4E (0.40) | KDM4ELMNAHPGDHSD17B10L3MBTL1 | |
| SCHEMBL31649199 | 0.80 | ACHE (0.39) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL31649031 | 0.79 | ACHE (0.41) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL3446185 | 0.78 | PTPN11 (0.46) | KDM4ELMNAHPGDHSD17B10ACHE | |
| SCHEMBL31649417 | 0.77 | PTPN11 (0.44) | LMNAHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL31649272 | 0.77 | KDM4E (0.34) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL31737273 | 0.77 | RBP4 (0.34) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL31737569 | 0.77 | RBP4 (0.34) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL31649144 | 0.77 | ALDH1A1 (0.41) | KDM4ELMNATP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20060074089-A1 | Quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074089-A1 | Quinolone analogs | NQO2, BAX, MCL1 | KDM4E 1268/4885NPC1 2053/4885LMNA 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.