Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444395 | 0.89 | KDM4E (0.48) | HTR1BADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL3445220 | 0.87 | ADRB2 (0.42) | HTR1BADRB2ADRB1ADRB3LMNA | |
| SCHEMBL2098846 | 0.84 | HPGD (0.48) | LMNACYP1A2ALDH1A1HTR2BTSHR | |
| SCHEMBL3445002 | 0.83 | HTR1B (0.42) | HTR1BNR2E1ADRB2ADRB1ADRB3 | |
| Dimethylamine SCHEMBL4364526 | 0.83 | ALDH1A1 (0.44) | HTR1BADRB2ADRB1ADRB3LMNA | |
| SCHEMBL4364851 | 0.81 | ALDH1A1 (0.41) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| SCHEMBL3444115 | 0.81 | KDM4E (0.39) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| Diethylamine SCHEMBL3445008 | 0.80 | ALDH1A1 (0.46) | HTR1BADRB2ADRB1LMNACYP1A2 | |
| SCHEMBL3446067 | 0.80 | ALDH1A1 (0.39) | HTR1BADRB2ADRB1ADRB3LMNA | |
| SCHEMBL3445326 | 0.80 | HTR1B (0.47) | HTR1BCYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816475-B2 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| EP-1829857-B1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20070213490-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION | 2007-09-13 | — | — | US | disclosed |
| EP-1829857-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | Tosoh Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |