Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 5/20 | 0.39 |
| ▸ | SKP1 | P63208 | 5/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730190 | 0.87 | CHRM4 (0.44) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL346152 | 0.84 | CKS1B (0.39) | CHRM4DGAT1CKS1BSKP1SKP2 | |
| SCHEMBL345491 | 0.83 | ENPP2 (0.43) | CHRM4DGAT1CKS1BSKP1SKP2 | |
| SCHEMBL1727687 | 0.78 | PDE10A (0.43) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL345057 | 0.77 | CHRM4 (0.57) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL344799 | 0.77 | PDE10A (0.55) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL26077359 | 0.76 | PDE10A (0.51) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL29207896 | 0.75 | PPARG (0.45) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL15205454 | 0.75 | CHRM4 (0.50) | CHRM4PDE10AAKR1C3PPARGPPARD | |
| SCHEMBL1727978 | 0.74 | KDM1A (0.43) | PPARGPPARADGAT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | INTS9, CDK8, SCN8A | CHRM4 1210/4885PDE10A 1799/4885AKR1C3 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.