Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727916 | 0.89 | ENPP2 (0.45) | ENPP2HRH3PANK3GPR119DGAT1 | |
| SCHEMBL1727578 | 0.88 | ENPP2 (0.42) | ENPP2HRH3PANK3DGAT1RORC | |
| SCHEMBL344553 | 0.83 | CHRM4 (0.47) | PANK3GPR119DGAT1CHRM4CKS1B | |
| SCHEMBL346152 | 0.80 | CKS1B (0.39) | GPR119DGAT1CHRM4CKS1BSKP1 | |
| SCHEMBL1728880 | 0.80 | CHRM4 (0.49) | ENPP2PANK3CHRM4 | |
| SCHEMBL345439 | 0.78 | ENPP2 (0.45) | ENPP2HRH3PANK3GPR119DGAT1 | |
| SCHEMBL1727913 | 0.77 | HRH3 (0.38) | ENPP2HRH3PANK3GPR119RORC | |
| SCHEMBL1727577 | 0.75 | PANK3 (0.38) | ENPP2HRH3PANK3GPR119RORC | |
| SCHEMBL9993631 | 0.73 | PANK3 (0.39) | ENPP2HRH3PANK3GPR119RORC | |
| SCHEMBL5234572 | 0.73 | PANK3 (0.55) | HRH3PANK3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | INTS9, CDK8, SCN8A | ENPP2 3085/4885HRH3 50/4885PANK3 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.