Dimethylamine

Dimethylamine

SCHEMBL4375978

C=Cc1cccc(OCCC)c1.CNC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.41
KDM4E B2RXH2 2/20 0.40
CHRNA7 P36544 2/20 0.40
NR1H4 Q96RI1 1/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DHFR P00374 1/20 0.40
GPBAR1 Q8TDU6 1/20 0.40
CYSLTR1 Q9Y271 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412110 0.95 KMT2A (0.50) TLR4TLR2KMT2ANPSR1TDP1
Dimethylamine SCHEMBL3445676 0.92 TLR4 (0.56) TLR4TLR2KMT2ANPSR1TSHR
Diethylamine SCHEMBL3454324 0.91 TLR4 (0.45) TLR4TLR2KMT2ANPSR1TDP1
Dimethylamine SCHEMBL3445667 0.91 TSHR (0.53) TLR4TLR2KMT2ATSHRNR1H4
Dimethylamine SCHEMBL4361280 0.89 TSHR (0.55) TLR4TLR2KMT2ATSHRDHFR
SCHEMBL3444152 0.88 ADRB2 (0.44) TLR4TLR2KMT2ANPSR1TDP1
SCHEMBL3446528 0.88 TLR4 (0.43) TLR4TLR2KMT2ANPSR1TDP1
SCHEMBL412094 0.87 TLR4 (0.60) TLR4TLR2KMT2ANPSR1TDP1
SCHEMBL4376033 0.86 ADRB2 (0.42) TLR4TLR2KMT2ANPSR1TDP1
SCHEMBL3444786 0.86 KMT2A (0.43) TLR4TLR2KMT2ANPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed