Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 5/20 | 0.40 |
| ▸ | ATP4B | P51164 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366446 | 0.94 | CHRNB2 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3445640 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3444993 | 0.84 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3444178 | 0.84 | TLR4 (0.45) | AHRKDM4EBCHEMAOAMAOB | |
| SCHEMBL413985 | 0.83 | CHRNB2 (0.66) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3444400 | 0.82 | MAOA (0.53) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3445157 | 0.82 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3445438 | 0.81 | MAOA (0.54) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL924891 | 0.80 | CHRNB2 (0.62) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3445500 | 0.79 | MAOA (0.56) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816475-B2 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| EP-1829857-B1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20070213490-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION | 2007-09-13 | — | — | US | disclosed |
| EP-1829857-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | Tosoh Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |