SCHEMBL3445837

SCHEMBL3445837

C=Cc1ccc(OCCCN(CCC)CC(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA7 P36544 1/20 0.47
CHRNA4 P43681 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
BCHE P06276 4/20 0.44
ACHE P22303 4/20 0.44
ATP4A P20648 6/20 0.43
ATP4B P51164 6/20 0.43
KDM4E B2RXH2 2/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446196 0.92 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3444402 0.89 MAOA (0.56) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3444158 0.87 CHRNB2 (0.47) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3445727 0.86 MAOA (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3445870 0.86 MAOA (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3444400 0.86 MAOA (0.53) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3446155 0.85 KDM4E (0.43) MAOAMAOBBCHEACHEKDM4E
SCHEMBL3444593 0.84 MAOA (0.61) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3445166 0.83 MAOA (0.64) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3445142 0.83 MAOA (0.64) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed