Phenanthroline

Phenanthroline

SCHEMBL344595

Cl[Pd]Cl.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.80
CCR8 P51685 5/20 0.80
LMNA P02545 4/20 0.80
CCR5 P51681 3/20 0.80
KDM4E B2RXH2 3/20 0.80
MMP2 P08253 2/20 0.80
TSHR P16473 2/20 0.80
MAPT P10636 2/20 0.80
HTT P42858 2/20 0.80
SMN1; SMN2 Q16637 2/20 0.80
TDP1 Q9NUW8 2/20 0.80
GMNN O75496 1/20 0.80
TP53 P04637 1/20 0.80
HSP90AA1 P07900 1/20 0.80
CYP3A4 P08684 1/20 0.80
CYP2D6 P10635 1/20 0.80
MMP9 P14780 1/20 0.80
ALOX15 P16050 1/20 0.80
NFKB1 P19838 1/20 0.80
MMP8 P22894 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthroline SCHEMBL30084726 1.00 CCR1 (0.80) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29367277 0.89 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29354015 0.89 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8845760 0.89 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8312 0.89 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL2813173 0.87 CCR1 (0.84) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL30945289 0.87 CCR1 (0.84) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL22982126 0.87 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL21300488 0.87 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL3896724 0.87 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103570697-B The method for preparing vilazodone and its intermediate 江苏先声药业有限公司 2017-09-15 CN claimed
CN-103664911-B The method for preparing vilazodone and its intermediate 江苏先声药业有限公司 2017-09-15 CN claimed
CN-104341370-A Preparation method of cetilistat SHANDONG CHUANGXIN PHARMACEUTICAL RES AND DEV CO LTD 2015-02-11 CN claimed
CN-103664911-A Method of preparing vilazodone and intermediate thereof JIANGSU SIMCERE PHARMACEUTICAL 2014-03-26 CN claimed
CN-103570697-A Method for preparing vilazodone and intermediate thereof JIANGSU SIMCERE PHARMACEUTICAL 2014-02-12 CN claimed
US-20110281894-A1 HEMIFUMARATE SALT ASTRAZENECA AB (SE) 2011-11-17 US claimed
CN-117295744-A Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing raw material therefor 明治制果药业株式会社 2023-12-26 CN disclosed
US-20220389310-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2022-12-08 US disclosed
CN-109715593-B Method for removing or recovering 2-alkoxyethanol and method for producing (2-alkoxyethyl) vinyl ether 丸善石油化学株式会社 2022-05-31 CN disclosed
US-11247961-B2 Me 1 hod for removing or collecting 2-alkoxyethanol, and method for producing (2-alkoxyethyl) vinyl ether MARUZEN PETROCHEMICAL CO., LTD. (JP) 2022-02-15 US disclosed
WO-2021062035-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2021-04-01 WO disclosed
US-10961213-B2 Process for preparation of benzylic amides BASF SE (DE) 2021-03-30 US disclosed
EP-3514133-B1 METHOD FOR REMOVING OR COLLECTING 2-ALKOXYETHANOL, AND METHOD FOR PRODUCING (2-ALKOXYETHYL) VINYL ETHER MARUZEN PETROCHEM CO LTD (JP) 2020-11-25 EP disclosed
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF FUJIFILM CORPORATION (JP) 2009-10-22 US disclosed
US-20090048413-A1 Method for Production of Conjugated Polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-19 US disclosed
EP-1997844-A1 METHOD FOR PRODUCTION OF CONJUGATED POLYMER Sumitomo Chemical Company, Limited (JP) 2008-12-03 EP disclosed
US-20070190435-A1 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-7119160-B2 Polyalkenyl ether resin KYOWA HAKKO CHEMICAL CO., LTD. (JP) 2006-10-10 US disclosed
US-20050176889-A1 Polyalkenyl ether resin KYOWA HAKKO CHEMICAL CO. LTD. (JP) 2005-08-11 US disclosed
US-20040185372-A1 Dye-containing curable composition, color filter, and process of preparing color filter FUJI PHOTO FILM CO., LTD. 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110281894-A1 HEMIFUMARATE SALT PSEN1, PSEN2, SNCA CCR1 4535/4885CCR8 4816/4885LMNA 747/4885
US-10961213-B2 Process for preparation of benzylic amides CYP2F1, BBOX1, F12 CCR1 4022/4885CCR8 4284/4885LMNA 1118/4885
US-20220389310-A1 LUMINESCENT MATERIALS AND METHODS THEREOF TYR, GSTA2, CYBA CCR1 4028/4885CCR8 3339/4885LMNA 1420/4885
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF L1CAM, PDCD1LG2, CD274 CCR1 732/4885CCR8 1545/4885LMNA 3890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.