SCHEMBL3445964

SCHEMBL3445964

O=C(O)C1(Cl)C=CC=C(Cl)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3526634 0.84
SCHEMBL9705858 0.82
SCHEMBL28484411 0.78 KDM4E (0.33)
SCHEMBL29896255 0.76
SCHEMBL28493610 0.72 HSD11B1 (0.30)
SCHEMBL28412438 0.70
SCHEMBL975623 0.67
SCHEMBL18525220 0.66
SCHEMBL978922 0.64
SCHEMBL13732952 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119999692-A Application of AZD8055 compound in improving activity of crop seeds 广州澄智澜生科技有限公司 2025-05-16 CN claimed
CN-111960996-A Preparation method of 4-amino-2, 6-dichloropyridine 杭州珠联医药科技有限公司 2020-11-20 CN claimed
CN-119999692-A Application of AZD8055 compound in improving activity of crop seeds 广州澄智澜生科技有限公司 2025-05-16 CN disclosed
CN-119912448-A AZD8055 derivative based on N-methyl-2-hydroxy ethylamine and application thereof 广州澄智澜生科技有限公司 2025-05-02 CN disclosed
CN-119912450-A AZD8055 derivative containing 5-amino-2, 6-piperidinedione and application thereof 广州澄智澜生科技有限公司 2025-05-02 CN disclosed
CN-119912451-A R-ureide compounds and uses thereof 广州澄智澜生科技有限公司 2025-05-02 CN disclosed
CN-119912449-A Compound containing 1, 4-diaza-cyclohexane piperazine and application thereof 广州澄智澜生科技有限公司 2025-05-02 CN disclosed
CN-111960996-A Preparation method of 4-amino-2, 6-dichloropyridine 杭州珠联医药科技有限公司 2020-11-20 CN disclosed
EP-1928887-B1 METHODS OF PREPARING QUINOLONE ANALOGS SENHWA BIOSCIENCES INC (TW) 2014-12-17 EP disclosed
US-7834180-B2 Methods of preparing quinolone analogs CYLENE PHARMACEUTICALS, INC. (US) 2010-11-16 US disclosed
US-7816406-B2 Quinolone analogs CYLENE PHARMACEUTICALS, INC. (US) 2010-10-19 US disclosed
US-7816524-B2 Methods of preparing quinolone analogs CYLENE PHARMACEUTICALS, INC. (US) 2010-10-19 US disclosed
US-20090082565-A1 METHODS OF PREPARING QUINOLONE ANALOGS CYLENE PHARMACEUTICALS, INC. (US) 2009-03-26 US disclosed
EP-1928887-A1 METHODS OF PREPARING QUINOLONE ANALOGS Cylene Pharmaceuticals, Inc. (US) 2008-06-11 EP disclosed
EP-1802306-A2 QUINOLONE ANALOG AS CELL PROLIFERATION INHIBITORS Cylene Pharmaceuticals, Inc. (US) 2007-07-04 EP disclosed
WO-2007019295-A1 METHODS OF PREPARING QUINOLONE ANALOGS CYLENE PHARMACEUTICALS, INC. (US) 2007-02-15 WO disclosed
US-20070032652-A1 Methods of preparing quinolone analogs SENHWA BIOSCIENCES, INC. (TW) 2007-02-08 US disclosed
US-20060074089-A1 Quinolone analogs SENHWA BIOSCIENCES, INC. (TW) 2006-04-06 US disclosed
WO-2006034113-A2 QUINOLONE ANALOGS AS CELL PROLIFERATION INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2006-03-30 WO disclosed