⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445964 | 0.84 | — | — | |
| SCHEMBL9705858 | 0.82 | — | — | |
| SCHEMBL28484411 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL28412438 | 0.70 | — | — | |
| SCHEMBL28493610 | 0.68 | HSD11B1 (0.30) | — | |
| SCHEMBL29896255 | 0.68 | — | — | |
| SCHEMBL18525220 | 0.66 | — | — | |
| SCHEMBL5667873 | 0.64 | — | — | |
| SCHEMBL13732952 | 0.63 | — | — | |
| SCHEMBL30304690 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928887-B1 | METHODS OF PREPARING QUINOLONE ANALOGS | SENHWA BIOSCIENCES INC (TW) | 2014-12-17 | — | — | EP | disclosed |
| US-7834180-B2 | Methods of preparing quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-7816524-B2 | Methods of preparing quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090082565-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | US | disclosed |
| EP-1928887-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | Cylene Pharmaceuticals, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007019295-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070032652-A1 | Methods of preparing quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2007-02-08 | — | — | US | disclosed |